Pathophysiology
cirrhosis is the scarring 1 of the liver resulting in balk to the work of blood and bile.
Causes: Excessive alcohol intake Alchoholic cirrhosis of the liver 2 Patho: Fatty liver, Causes: Biliary Cirrhosis New node
Hepatic obstruction of blood flow Patho: Obstruction of bile flolw Causes: Autoimmune mechanisms autochthonic Biliary Patho: tinder/scarring of lobular bile ducts Causes:
Physical trial run 6
Blood Tests CT Scan/ Ultrasound of the liver Liver Biospy During Surgery Abnormal liver funtion tests 5 Elevated blood serum enzymes and bilirubin Decreased serum albumin Prolonged PT Liver biospy Secondary Biliary
Diagnosis/Evaluation
Types of Cirrhosis
Obstruction via neoplasms, strictures, or gallstones Patho: irritation/scarring of bile ducts proximal to obstruction Causes:
Liver Tests Performed
Viral hepatitis Postnecrotic Cirrhosis Patho: Cirrhosis tissue replaces necrotic tissue
Cirrhosis
Alcohol cessation 4 Rest Vitamin supplements Nutritional diet Ascites Gastrointestinal bleeding encephalopathy Steroids Antiviral Meds: Hepatitis related Diuretics: Ascites Lactulose Medications Enlarged liver 3 Anorexia malady Jaundice Managment of complications: Metabolic Cirrhosis
Causes: Metabolic defects such as: Wilson disease, galactosemia, etc.
Patho: Inflammation/scarring with specific changes as related to cause
Treatment
Clinical Manifestations/Complications
Edema pyrexia Abdominal Pain Anemia Hepatomegaly, Splenomegaly, Hepatic encephalopathy, Portal HTN Acites
Notes
1) Cirrhosis is the scarring of the liver resulting in obstruction to the flow of blood and bile.
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